The performance effect will be the same as when you will create the dependencies manually. We just added instrumentation for scripting, which doesn't add any kind of increase on performance.
The hit will depend on character of the dependencies. I mean e.g. Dependency between two interfaces won't be as heavy as between two groups, so it's not easy to forecast.
But if the question was "Will adding of dependencies increase the load on server?" The answer is "YES".